Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10
Enjoy 10% OFF your first purchase ! Code: WELCOME10





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Already sold out in Korea, this cream was co-developed with Japanese influencer Nana after 7 months of intensive development. Designed to visibly restore compromised skin barriers caused by frequent professional treatments or intensive active care. Clinical testing by the Korea Institute of Dermatological Sciences showed 25.56% improvement in skin plumpness and elasticity after immediate use, 46.28% reduction in transepidermal water loss, and 9.44% visible improvement in dark spots after one week.
At the core is TECA-PDRN, combining Dongkook Pharmaceutical's patented Centella Asiatica extract with 2000 ppm PDRN and rose water. The 5D-PDRN Complex derived from salmon, Centella Asiatica, heartleaf, rose, and marine sources makes this the most advanced member of the Madeca Cream family. Clinically proven to reduce skin heat caused by sensitivity by up to 6.33 degrees C after a single application, while visibly soothing puffiness and discomfort.
The TECA-PDRN complex combines salmon DNA with Centella Asiatica actives for calming, plumping, and barrier repair in one step.
Clinically tested by the Korea Institute of Dermatological Sciences. Also showed 46.28% reduction in transepidermal water loss.
Derived from five sources: salmon, Centella Asiatica, heartleaf, rose, and marine ingredients for comprehensive renewal.
Clinically proven to reduce skin heat from sensitivity after a single application, soothing redness and discomfort.
Apply as the final step after cleansing, toning, and serum.
Apply a generous amount and gently pat into skin.
Use morning and evening for continuous barrier repair.
Especially effective after professional treatments or intensive active care nights.
Water, Glycerin, Methylpropanediol, Niacinamide, Dimethicone, Cyclopentasiloxane, Hydrogenated Poly(C6-12 Olefin), 1,2-Hexanediol, Caprylic/Capric Triglyceride, Glyceryl Stearate, Cetearyl Alcohol, Polyglyceryl-6 Distearate, Polysorbate 60, Madecassoside, Asiaticoside, Madecassic Acid, Asiatic Acid, Sodium DNA, Butylene Glycol, Panthenol, Allantoin, Adenosine, Beta-Glucan, Ceramide NP, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate, Hydrolyzed Sodium Hyaluronate Crosspolymer, Rosa Canina Fruit Extract, Centella Asiatica Extract, Houttuynia Cordata Extract, Ethylhexylglycerin, Disodium EDTA, Hydroxyacetophenone, Xanthan Gum, Carbomer, Tromethamine
PDRN (Polydeoxyribonucleotide) is a purified form of salmon DNA that supports skin renewal, helps soothe inflammation, and improves skin plumpness and elasticity. This cream contains 2000 ppm PDRN for intensive repair.
It was specifically developed for post-treatment skin, those who use strong active ingredients, or anyone with frequent sensitivity, redness, and barrier disruption.
A newly developed combination of Dongkook Pharmaceutical's patented Centella Asiatica extract (TECA) with 2000 ppm PDRN and rose water for synergistic calming and barrier repair.
Yes. Apply as the final step morning and evening. It is especially beneficial after professional treatments or heavy active care routines.
It refers to PDRN derived from five different sources: salmon, Centella Asiatica, heartleaf, rose, and marine-origin ingredients, making it the most comprehensive PDRN formula in the Madeca Cream line.
An advanced barrier repair cream with 2000ppm PDRN, TECA complex, and 10-type hyaluronic acid that soothes sensitivity, restores elasticity, and brightens skin.
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