Mary & May Smart Retinol™ Spicule PDRN Retinol Cream – Advanced Multi-Action Anti-Aging Treatment (15g)

Spicule x Retinol x PDRN: The New Era of Skin Renewal

Discover the future of retinol skincare with Mary & May Smart Retinol™ Spicule PDRN Cream, a next-generation anti-aging formula that combines Smart Retinol™, Spicule Micro-Delivery Technology, and PDRN for visible transformation in firmness, texture, and radiance — all with minimal irritation.

Harnessing the power of 200,000 micro-spicules, this cream delivers active ingredients deep into the skin to stimulate collagen production and accelerate cell renewal. Smart Retinol™ technology ensures a controlled, sustained release for faster results with reduced sensitivity, while PDRN (Sodium DNA) supports regeneration at the cellular level for improved elasticity and smoother texture.

The result? Firmer, brighter, and more even-toned skin — without dryness or flaking. Perfect for those looking to treat fine lines, wrinkles, uneven tone, enlarged pores, and dullness in a gentle yet effective way.

Infused with Niacinamide, Panthenol (2%), Adenosine, and Ceramide NP, this intelligent formula not only targets aging but also soothes and strengthens the skin barrier. Enriched with Shea Butter, Macadamia Oil, and Vitamin E, it nourishes deeply while protecting against oxidative stress.

Dermatologist-tested, fragrance-free, and suitable for sensitive skin — this is the ultimate smart retinol experience that’s both powerful and skin-friendly

• 4-in-1 Advanced Care – Targets fine lines, uneven tone, pores, and elasticity

• Smart Retinol™ Controlled Release – Delivers retinol gradually to minimize irritation

• Spicule Micro-Delivery System – 200,000 micro-spicules enhance absorption and boost renewal

• PDRN & Peptide Support – Stimulate collagen and accelerate regeneration

• Panthenol + Niacinamide – Calm, hydrate, and brighten the skin

• Barrier Repair Complex – Ceramide NP, Cholesterol, and Hyaluronic Acid restore moisture balance

• Visible Results – Pore and tone improvement in 4 weeks; fine line reduction in 8 weeks

• Retinol (0.1%) – Stimulates cell turnover and collagen for smoother, youthful skin

• PDRN (Sodium DNA) – Repairs and revitalizes at the cellular level for elasticity and renewal

• Niacinamide – Brightens, evens tone, and minimizes pores

• Panthenol (Vitamin B5) – Deeply hydrates and soothes irritation

• Adenosine – Firms and reduces the appearance of wrinkles

• Shea Butter & Macadamia Oil – Nourish and soften the skin

• Ceramide NP & Hyaluronic Acid – Strengthen and moisturize the skin barrier

1. Apply in the evening after cleansing and toning.

2. Gently spread a small amount (pea-sized) over the face, avoiding the eye area.

3. Follow with a moisturizer for added hydration.

4. For beginners, start 2–3 times per week, gradually increasing frequency as your skin builds tolerance.

5. Always apply sunscreen the following morning when using retinol products.

Precautions: Not recommended for use during pregnancy or breastfeeding. For external use only. Avoid contact with eyes. Discontinue if irritation occurs.